Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21867671 | 0.91 | SIRT1 (0.65) | SIRT1SRD5A2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2748306 | 0.84 | KCNK9 (0.47) | SIRT1SRD5A2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL30924444 | 0.82 | SIRT1 (0.65) | SIRT1SRD5A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21230531 | 0.81 | SIRT1 (0.56) | SIRT1SRD5A2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL23396621 | 0.81 | SRD5A2 (0.70) | SIRT1SRD5A2SMN1; SMN2LMNATYR | |
| SCHEMBL7482370 | 0.81 | SRD5A2 (0.70) | SIRT1SRD5A2SMN1; SMN2LMNATYR | |
| SCHEMBL10395127 | 0.78 | LMNA (0.71) | SRD5A2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL698836 | 0.78 | LMNA (0.71) | SRD5A2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10938928 | 0.78 | MAPT (0.71) | LMNAMEN1KMT2ATYRHTT | |
| SCHEMBL19160290 | 0.77 | KCNK9 (0.42) | SIRT1SRD5A2SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018077967-A1 | FLUOROPOLYMER LAMINATE FOR THERMOFORMING INTO VEHICLES BODY PANELS | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2018-05-03 | — | — | WO | disclosed |