SCHEMBL20101702

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18254635	0.88	PIN1 (0.48)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL21160447	0.86	PIN1 (0.47)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL21036999	0.86	PIN1 (0.51)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL15372394	0.86	PIN1 (0.64)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL3720508	0.84	MGMT (0.52)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL23764883	0.84	PIN1 (0.49)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL1533391	0.83	MPO (0.61)	PIN1MPOMGMTCYP3A4CDK1
	6-O-Benzylguanine SCHEMBL29405347	0.83	MGMT (0.63)	PIN1MPOMGMTCYP3A4CDK1
	6-O-Benzylguanine SCHEMBL600698	0.83	MGMT (0.63)	PIN1MPOMGMTCYP3A4CDK1
	SCHEMBL22871792	0.82	PIN1 (0.48)	PIN1MPOMGMTCYP3A4CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.