Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 7/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 7/20 | 0.46 |
| ▸ | TPO | P07202 | 1/20 | 0.45 |
| ▸ | EPX | P11678 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064122 | 0.90 | MGMT (0.67) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| SCHEMBL27090535 | 0.89 | PIN1 (0.47) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| SCHEMBL21036999 | 0.88 | PIN1 (0.51) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| SCHEMBL15372394 | 0.88 | PIN1 (0.64) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| SCHEMBL1533391 | 0.88 | MPO (0.61) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| 6-O-Benzylguanine SCHEMBL29405347 | 0.87 | MGMT (0.63) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| 6-O-Benzylguanine SCHEMBL600698 | 0.87 | MGMT (0.63) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| 6-O-Benzylguanine SCHEMBL4631743 | 0.86 | MGMT (0.61) | MGMTPIN1CYP3A4CDK1CCNB1 | |
| SCHEMBL12252582 | 0.86 | PIN1 (0.49) | MGMTPIN1LMNAMPO | |
| SCHEMBL23764883 | 0.85 | PIN1 (0.49) | MGMTPIN1CYP3A4CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164986-A | SNAP-tag-based cell membrane fluorescent dye and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | claimed |
| CN-110272437-B | Visible light-operated SNAP protein tag acid-resistant fluorescent molecular switch and synthesis thereof | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | claimed |
| CN-110272432-A | A kind of light-operated role in fluorescent molecule switch of acid resistance and its synthetic method and application | 中国科学院大连化学物理研究所 | 2019-09-24 | — | — | CN | claimed |
| US-12552938-B2 | Deuterated fluorophores | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2026-02-17 | — | — | US | disclosed |
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-01 | — | — | US | disclosed |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-09-11 | — | — | US | disclosed |
| US-12344594-B2 | Red-shifted fluorophores | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-07-01 | — | — | US | disclosed |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-04-10 | — | — | US | disclosed |
| WO-2024156920-A1 | FLUOROGENIC POLYMETHINE DYES | Universität Zürich (CH) | 2024-08-02 | — | — | WO | disclosed |
| US-12018157-B2 | Tunable photoactivatable silicon rhodamine fluorophores | SPIROCHROME AG (CH) | 2024-06-25 | — | — | US | disclosed |
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | CIS BIO INTERNATIONAL (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | CIS BIO INTERNATIONAL (FR) | 2011-09-29 | — | — | US | disclosed |
| US-7825096-B2 | O6-alkylguanine-DNA alkyltransferase inactivators and beta-glucuronidase cleavable prodrugs | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-11-02 | — | — | US | disclosed |
| US-7799524-B2 | Substrates for O6-alkylguanina-DNA alkyltransferase | Ecole Polytechnique Ferdeale de Lausanne (CH) | 2010-09-21 | — | — | US | disclosed |
| US-7799524-B2 | Substrates for O6-alkylguanina-DNA alkyltransferase | Ecole Polytechnique Ferdeale de Lausanne (CH) | 2010-09-21 | — | — | US | disclosed |
| WO-2010070232-A1 | NOVEL RARE EARTH ELEMENT CRYPTATES INCLUDING A TETRAAZATRIPHENYLENE UNIT | CIS BIO INTERNATIONAL (FR) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070232-A1 | NOVEL RARE EARTH ELEMENT CRYPTATES INCLUDING A TETRAAZATRIPHENYLENE UNIT | CIS BIO INTERNATIONAL (FR) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010034931-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | CIS-BIO INTERNATIONAL (FR) | 2010-04-01 | — | — | WO | disclosed |
| US-20070213279-A1 | O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATORS AND BETA-GLUCURONIDASE CLEAVABLE PRODRUGS | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | OGG1, UNG, MPG | MGMT 11/4885PIN1 1777/4885CYP3A4 2104/4885 |
| US-12344594-B2 | Red-shifted fluorophores | TFEB, DDX21, CDC73 | MGMT 2937/4885PIN1 1521/4885CYP3A4 1715/4885 |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | TFEB, DDX21, CDC73 | MGMT 2936/4885PIN1 1522/4885CYP3A4 1715/4885 |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | MSN, CHN2, EFHD2 | MGMT 1079/4885PIN1 4683/4885CYP3A4 1798/4885 |
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | AOC2, H1-2, CHAT | MGMT 1589/4885PIN1 4752/4885CYP3A4 1606/4885 |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | PFAS, FLI1, ARFGEF1 | MGMT 1486/4885PIN1 1425/4885CYP3A4 301/4885 |
| US-20070213279-A1 | O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATORS AND BETA-GLUCURONIDASE CLEAVABLE PRODRUGS | UNG, OGG1, MPG | MGMT 23/4885PIN1 3749/4885CYP3A4 734/4885 |
| US-12552938-B2 | Deuterated fluorophores | CTNND1, DRD1, DRD2 | MGMT 508/4885PIN1 391/4885CYP3A4 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.