SCHEMBL20102176

SCHEMBL20102176

C=CC(=O)OC(C)c1c(C)cc(C)cc1C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
HCAR2 Q8TDS4 1/20 0.33
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
ALDH1A1 P00352 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102165 0.83 HCAR2 (0.39) TSHRHCAR2HPGDALDH1A1KDM4E
SCHEMBL28758397 0.78 TSHR (0.39) TSHRHPGDNPSR1MCOLN3ALDH1A1
SCHEMBL14212573 0.74 HCAR2 (0.35) HCAR2
SCHEMBL28319485 0.73 HCAR2 (0.32) TSHRHCAR2
SCHEMBL10389193 0.73 TSHR (0.38) TSHRHCAR2
SCHEMBL11403625 0.73 TSHR (0.38) TSHRHCAR2
SCHEMBL21314239 0.72 HCAR2 (0.33) TSHRHCAR2ALDH1A1
SCHEMBL6536970 0.72 HCAR2 (0.53) TSHRHCAR2HPGDALDH1A1KDM4E
SCHEMBL3684997 0.71 HCAR2 (0.41) TSHRHCAR2ALDH1A1KDM4E
SCHEMBL20102177 0.71 FGFR4 (0.38) TSHRHCAR2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10739678-B2 Photocurable composition, pattern forming method, and method for manufacturing device FUJIFILM CORPORATION (JP) 2020-08-11 US disclosed
US-20180120698-A1 PHOTOCURABLE COMPOSITION, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-20180120698-A1 PHOTOCURABLE COMPOSITION, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed