SCHEMBL20102165

SCHEMBL20102165

C=CC(=O)OC(C)c1c(C)cccc1C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.39
TSHR P16473 2/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
THRB P10828 4/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 5/20 0.32
HSD17B10 Q99714 3/20 0.32
KDM4E B2RXH2 3/20 0.31
SCN4A P35499 2/20 0.31
HPGD P15428 2/20 0.31
THRA P10827 1/20 0.31
NR4A2 P43354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102176 0.83 TSHR (0.35) HCAR2TSHRALDH1A1KDM4EHPGD
SCHEMBL28200013 0.82 HCAR2 (0.40) HCAR2TSHRCA1CA2CA7
SCHEMBL20102177 0.81 FGFR4 (0.38) HCAR2TSHRALDH1A1HPGD
SCHEMBL3684997 0.81 HCAR2 (0.41) HCAR2TSHRTHRBALDH1A1KDM4E
SCHEMBL20102173 0.78 CTSS (0.37) HCAR2ALDH1A1
SCHEMBL11029507 0.76 ALDH1A1 (0.40) TSHRL3MBTL1ALDH1A1HPGD
SCHEMBL6536970 0.76 HCAR2 (0.53) HCAR2TSHRCA1CA2CA7
SCHEMBL28863896 0.75 HCAR2 (0.67) HCAR2THRBALDH1A1HSD17B10HPGD
SCHEMBL41557 0.75 HCAR2 (0.67) HCAR2THRBALDH1A1HSD17B10HPGD
SCHEMBL11636414 0.74 HCAR2 (0.39) HCAR2THRBL3MBTL1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10739678-B2 Photocurable composition, pattern forming method, and method for manufacturing device FUJIFILM CORPORATION (JP) 2020-08-11 US disclosed
US-20180120698-A1 PHOTOCURABLE COMPOSITION, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-20180120698-A1 PHOTOCURABLE COMPOSITION, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed