SCHEMBL20102333

SCHEMBL20102333

COC(=O)Cn1c2c(sc1=O)C(=O)CN(BC=O)C2

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102332 0.79 KDM4E (0.32) KDM4ESMN1; SMN2
SCHEMBL20102335 0.79
SCHEMBL20102326 0.74
SCHEMBL24703554 0.59 KDM4E (0.57) KDM4ESMN1; SMN2
SCHEMBL11740900 0.56 L3MBTL1 (0.65) KDM4ESMN1; SMN2
SCHEMBL7340852 0.55 KDM4E (0.52) KDM4ESMN1; SMN2
SCHEMBL16727947 0.55 BRD4 (0.42) SMN1; SMN2
SCHEMBL20022770 0.55
SCHEMBL14564387 0.54 ALDH1A1 (0.57) KDM4ESMN1; SMN2
SCHEMBL4938578 0.53 ALDH1A1 (0.59) KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118765-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS MUTABILIS (FR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118765-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS NQO1, PEPD, LCT KDM4E 3033/4885SMN1; SMN2 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.