Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20102408 | 0.82 | THRB (0.39) | THRATHRBESR1 | |
| SCHEMBL17770797 | 0.81 | TLR8 (0.40) | TLR8THRATHRBESR1MCHR1 | |
| SCHEMBL17770796 | 0.80 | TLR8 (0.41) | TLR8THRATHRBESR1MCHR1 | |
| SCHEMBL20102409 | 0.79 | ESR1 (0.38) | THRATHRBESR1L3MBTL1 | |
| SCHEMBL20102413 | 0.78 | THRB (0.39) | THRATHRBESR1 | |
| SCHEMBL17770800 | 0.77 | TLR8 (0.38) | TLR8ESR1MCHR1L3MBTL1 | |
| SCHEMBL20102390 | 0.75 | L3MBTL1 (0.42) | THRATHRBL3MBTL1 | |
| SCHEMBL17771257 | 0.74 | TLR8 (0.40) | TLR8ESR1MCHR1L3MBTL1 | |
| SCHEMBL20102417 | 0.74 | THRB (0.38) | THRATHRBESR1 | |
| SCHEMBL17770799 | 0.73 | TLR8 (0.37) | TLR8MCHR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119009-A1 | LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180119009-A1 | LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | YBX1, PIEZO1, C1S | TLR8 4367/4885THRA 3521/4885THRB 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.