Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009729 | 0.87 | MAOB (0.56) | MAOBPPARAALKBH1MRGPRX4FFAR1 | |
| SCHEMBL1756377 | 0.82 | MRGPRX4 (0.65) | PPARAMRGPRX4NR4A2 | |
| SCHEMBL2010830 | 0.81 | MAOB (0.50) | MAOBPPARAFFAR1FFAR4GSK3B | |
| SCHEMBL23978033 | 0.80 | MRGPRX4 (0.69) | MAOBPPARAMRGPRX4NR4A2PARP15 | |
| SCHEMBL1756330 | 0.80 | GYS1 (0.54) | MRGPRX4ALDH1A1GAA | |
| SCHEMBL411705 | 0.78 | BCL2L1 (0.62) | MAP4K4ALDH1A1GAA | |
| SCHEMBL2009537 | 0.78 | MAOB (0.46) | MAOBFFAR1FFAR4GSK3BBACE1 | |
| SCHEMBL11101459 | 0.76 | ESR1 (0.51) | MAOBFFAR1FFAR4MAP4K4ALDH1A1 | |
| SCHEMBL31530144 | 0.76 | MRGPRX4 (0.53) | MAOBPPARAALKBH1MRGPRX4NR4A2 | |
| SCHEMBL19140236 | 0.75 | FFAR4 (0.56) | MAOBPPARAALKBH1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| US-20110136792-A1 | NOVEL CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | BOLIN DAVID ROBERT | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136792-A1 | NOVEL CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | GYS2, GYS1, PYGL | MAOB 1010/4885PPARA 299/4885ALKBH1 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.