Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 13/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009537 | 0.88 | MAOB (0.46) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL2030541 | 0.84 | MAOB (0.44) | MAOBFFAR4FFAR1GRM5F10 | |
| SCHEMBL5514364 | 0.82 | MAOB (0.62) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL2010283 | 0.81 | MAOB (0.56) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL2009729 | 0.78 | MAOB (0.56) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL18310473 | 0.74 | GRM5 (0.46) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL7024313 | 0.74 | CACNA1C (0.53) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL14762631 | 0.73 | CACNA1C (0.50) | MAOBFFAR4FFAR1GSK3BBACE1 | |
| SCHEMBL16841041 | 0.73 | MAOB (0.51) | MAOBGRM5F10 | |
| SCHEMBL12737130 | 0.73 | FFAR1 (0.47) | MAOBFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| US-20110136792-A1 | NOVEL CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | BOLIN DAVID ROBERT | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136792-A1 | NOVEL CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | GYS2, GYS1, PYGL | MAOB 1010/4885FFAR4 747/4885FFAR1 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.