SCHEMBL20103100

SCHEMBL20103100

O=C(CCl)OC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABHD6 Q9BV23 6/20 0.34
MGLL Q99685 2/20 0.34
PLA2G7 Q13093 1/20 0.34
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13411205 0.84 CA1 (0.32) CA1CA2CA9
SCHEMBL14338617 0.80 ABHD6 (0.33) ABHD6MGLLPLA2G7CA1CA2
SCHEMBL21432374 0.78 ABHD6 (0.32) ABHD6MGLLPLA2G7CA1CA2
SCHEMBL20100481 0.77 FAAH (0.32)
SCHEMBL13446323 0.77
SCHEMBL22006641 0.76 LMNA (0.42)
SCHEMBL21421512 0.76 TRPA1 (0.36) ABHD6MGLLPLA2G7CA1CA2
SCHEMBL26339931 0.76 HTT (0.33) ABHD6MGLLPLA2G7CA1CA2
SCHEMBL4387367 0.76 MEN1 (0.36) ABHD6MGLLPLA2G7CA1CA2
SCHEMBL22007563 0.74 LMNA (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed