Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103161 | 0.81 | HPGD (0.43) | P2RX7ALDH1A1POLBPARP1 | |
| SCHEMBL22816934 | 0.81 | ALDH1A1 (0.60) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL22816936 | 0.80 | HSD17B10 (0.42) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8305486 | 0.80 | HSD17B10 (0.45) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL14048348 | 0.78 | HSD17B10 (0.50) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4480763 | 0.78 | SRD5A1 (0.42) | MEN1KMT2AALDH1A1HTTPOLB | |
| SCHEMBL9360420 | 0.78 | ADRA1B (0.51) | P2RX7GAAALDH1A1PARP1 | |
| SCHEMBL20103130 | 0.78 | ADRA1A (0.48) | P2RX7ALDH1A1POLB | |
| SCHEMBL2193401 | 0.78 | KMT2A (0.47) | P2RX7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL24928510 | 0.77 | HSD17B10 (0.44) | GAAMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078005-A1 | AMIDO-SUBSTITUTED AZASPIRO DERIVATIVES AS TANKYRASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |