Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 4/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103531 | 0.85 | PDK1 (0.48) | PTPRBCTRB1LOXL2MEN1KMT2A | |
| SCHEMBL1067890 | 0.84 | PTPRB (0.41) | PTPRBLOXL2MAOAMAOBALDH1A1 | |
| SCHEMBL20103561 | 0.84 | CYP4F2 (0.43) | PTPRBCTRB1LOXL2MEN1KMT2A | |
| SCHEMBL28808224 | 0.82 | CTRB1 (0.50) | PTPRBCTRB1ALDH1A1MEN1KMT2A | |
| SCHEMBL20103651 | 0.80 | PTPRB (0.39) | PTPRBCTRB1LOXL2MEN1KMT2A | |
| SCHEMBL20103512 | 0.78 | PTPRB (0.46) | PTPRBMEN1KMT2A | |
| SCHEMBL11323686 | 0.77 | PTPRB (0.37) | PTPRBLOXL2MAOAMAOBALDH1A1 | |
| SCHEMBL27493258 | 0.77 | SMN1; SMN2 (0.37) | PTPRBLOXL2MAOAMAOBALDH1A1 | |
| SCHEMBL11323681 | 0.77 | PTPRB (0.37) | PTPRBLOXL2MAOAMAOBALDH1A1 | |
| SCHEMBL20103363 | 0.75 | ESR1 (0.38) | PTPRBCTRB1LOXL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |