Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103561 | 0.87 | CYP4F2 (0.43) | PDK1PDK2PDK3PDK4PTPRB | |
| SCHEMBL20103587 | 0.85 | PTPRB (0.40) | PTPRBCTRB1MEN1KMT2AMRGPRX4 | |
| SCHEMBL20103651 | 0.83 | PTPRB (0.39) | PDK1PDK2PDK3PDK4PTPRB | |
| SCHEMBL28808224 | 0.82 | CTRB1 (0.50) | PTPRBCTRB1MEN1KMT2APTPN1 | |
| SCHEMBL20103512 | 0.78 | PTPRB (0.46) | PDK1PDK2PDK3PDK4PTPRB | |
| SCHEMBL20103363 | 0.75 | ESR1 (0.38) | PTPRBCTRB1MEN1KMT2AMRGPRX4 | |
| SCHEMBL10294037 | 0.73 | ENPP2 (0.45) | PDK1PDK2PDK3PDK4IKBKB | |
| SCHEMBL20103538 | 0.72 | RECQL (0.45) | MRGPRX4LOXL2 | |
| SCHEMBL19776008 | 0.72 | PPARA (0.43) | PTPRBCTRB1MEN1KMT2APTPN1 | |
| SCHEMBL2139015 | 0.72 | CYP3A4 (0.49) | PDK1PDK2PDK3PDK4REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |