Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12853821 | 0.73 | ALOX5 (0.46) | ALOX5TRPM8HCAR3CETPALDH1A1 | |
| SCHEMBL968495 | 0.73 | LMNA (0.48) | ALDH1A1CNR2 | |
| SCHEMBL12853946 | 0.72 | ALOX5 (0.53) | ALOX5TRPM8HCAR3CETPALDH1A1 | |
| SCHEMBL29953793 | 0.71 | ALOX5 (0.45) | ALOX5TRPM8HCAR3CETPALDH1A1 | |
| SCHEMBL16708762 | 0.70 | USP2 (0.42) | ALDH1A1MAPTMEN1KMT2ARECQL | |
| SCHEMBL28226951 | 0.70 | TRPM8 (0.57) | ALOX5TRPM8HCAR3CETPALDH1A1 | |
| SCHEMBL9367244 | 0.70 | — | — | |
| SCHEMBL13103949 | 0.69 | TRPM8 (0.43) | ALOX5TRPM8HCAR3CETPSLC1A3 | |
| SCHEMBL21392853 | 0.69 | TRPM8 (0.52) | ALOX5TRPM8HCAR3CETPALDH1A1 | |
| SCHEMBL28226280 | 0.69 | TRPM8 (0.67) | ALOX5TRPM8HCAR3CETPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |