Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952316 | 0.83 | ALOX5 (0.42) | ALOX5TRPM8HCAR3CHRM2CHRM1 | |
| SCHEMBL12853821 | 0.77 | ALOX5 (0.46) | ALOX5TRPM8HCAR3ALDH1A1CXCR3 | |
| SCHEMBL9367244 | 0.74 | — | — | |
| SCHEMBL265489 | 0.73 | ALDH1A1 (0.52) | PYCR1ALDH1A1 | |
| SCHEMBL7262869 | 0.72 | — | — | |
| SCHEMBL20104061 | 0.71 | ALOX5 (0.45) | ALOX5TRPM8HCAR3CHRM2CHRM1 | |
| SCHEMBL29956348 | 0.70 | KDM4E (0.42) | PYCR1ALDH1A1 | |
| SCHEMBL29950568 | 0.68 | HSD11B1 (0.44) | TRPM8HCAR3PYCR1ALDH1A1MAPT | |
| SCHEMBL29953362 | 0.68 | RIPK1 (0.45) | ALOX5ALDH1A1MAPT | |
| SCHEMBL19910402 | 0.67 | CYP2D6 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |