Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20105008 | 0.92 | CCNB2 (0.46) | CNR1LMNAGAAMAPTOPRM1 | |
| SCHEMBL20105037 | 0.89 | HSP90AA1 (0.47) | CNR1LMNAGAAMAPTKIF11 | |
| SCHEMBL20105028 | 0.88 | CNR1 (0.50) | CNR1LMNAGAAMAPTHSP90AA1 | |
| SCHEMBL20105014 | 0.87 | CNR1 (0.53) | CNR1LMNAGAAMAPTOPRM1 | |
| SCHEMBL21272280 | 0.84 | CNR1 (0.55) | CNR1LMNAMAPTOPRM1OPRD1 | |
| SCHEMBL20105010 | 0.80 | MIF (0.43) | CNR1LMNAGAAMAPTOPRM1 | |
| SCHEMBL20105033 | 0.79 | CCNB2 (0.48) | CNR1LMNAGAAMAPTOPRM1 | |
| SCHEMBL20105042 | 0.77 | CCNB2 (0.53) | CNR1LMNAGAAMAPTHSP90AA1 | |
| SCHEMBL5262177 | 0.77 | MAPT (0.56) | CNR1LMNAMAPTCNR2 | |
| SCHEMBL20105040 | 0.74 | MAPT (0.52) | CNR1LMNAGAAMAPTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-22 | — | — | US | claimed |
| US-10597362-B2 | 3-aminoalkylated indole derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2020-03-24 | — | — | US | disclosed |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-22 | — | — | US | disclosed |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-22 | — | — | US | disclosed |
| WO-2018080215-A1 | 3-AMINO ALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597362-B2 | 3-aminoalkylated indole derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | IDO1, TPH1, AADAT | CNR1 457/4885LMNA 2385/4885GAA 3972/4885 |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | IDO1, TPH1, AADAT | CNR1 457/4885LMNA 2385/4885GAA 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.