Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20105014 | 0.92 | CNR1 (0.53) | CHRM2ADRA2ACHRM1DRD1DRD3 | |
| SCHEMBL21272281 | 0.89 | CHRM2 (0.52) | CCNB2CDK1CCNB1CCNB3CHRM2 | |
| SCHEMBL20105008 | 0.88 | CCNB2 (0.46) | CCNB2CDK1CCNB1CCNB3CNR1 | |
| SCHEMBL20105026 | 0.87 | CHRM2 (0.58) | CCNB2CDK1CCNB1CCNB3CHRM2 | |
| SCHEMBL20105038 | 0.84 | CHRM2 (0.60) | CCNB2CDK1CCNB1CCNB3CHRM2 | |
| SCHEMBL20105043 | 0.83 | CHRM2 (0.53) | CCNB2CDK1CCNB1CCNB3CHRM2 | |
| SCHEMBL20105031 | 0.82 | CHRM2 (0.49) | CCNB2CDK1CCNB1CCNB3CHRM2 | |
| SCHEMBL20105030 | 0.80 | HTR2A (0.56) | CHRM2ADRA2ACHRM1DRD1DRD3 | |
| SCHEMBL20105040 | 0.80 | MAPT (0.52) | CHRM2ADRA2ACHRM1DRD1DRD3 | |
| SCHEMBL20105011 | 0.79 | CNR1 (0.53) | CNR1OPRM1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597362-B2 | 3-aminoalkylated indole derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2020-03-24 | — | — | US | claimed |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-22 | — | — | US | claimed |
| US-10597362-B2 | 3-aminoalkylated indole derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2020-03-24 | — | — | US | disclosed |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-22 | — | — | US | disclosed |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-22 | — | — | US | disclosed |
| WO-2018080215-A1 | 3-AMINO ALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597362-B2 | 3-aminoalkylated indole derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | IDO1, TPH1, AADAT | CCNB2 3697/4885CDK1 2609/4885CCNB1 2930/4885 |
| US-20190256465-A1 | 3-AMINOALKYLATED INDOLE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | IDO1, TPH1, AADAT | CCNB2 3697/4885CDK1 2609/4885CCNB1 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.