Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696096 | 0.79 | PTPN5 (0.46) | CLK4FFAR1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL4595908 | 0.78 | GSK3B (0.58) | CLK4PRKACACDK8CLK2GSK3A | |
| SCHEMBL7102889 | 0.77 | FFAR1 (0.62) | FFAR1ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL22853455 | 0.77 | KDM4E (0.60) | CLK4PRKACACDK8CLK2GSK3A | |
| SCHEMBL29876988 | 0.75 | KIF11 (0.53) | ALDH1A1MAPTSMN1; SMN2TDP1AR | |
| SCHEMBL6696407 | 0.72 | HSD17B10 (0.50) | CLK4PRKACACDK8CLK2GSK3A | |
| SCHEMBL6561038 | 0.72 | PTPN5 (0.67) | ALDH1A1MAPTSMN1; SMN2TDP1TSHR | |
| SCHEMBL22273618 | 0.72 | MAP3K8 (0.53) | CLK4PRKACACDK8CLK2GSK3A | |
| SCHEMBL20183521 | 0.72 | HSD17B10 (0.53) | CLK4PRKACACDK8CLK2GSK3A | |
| SCHEMBL12275756 | 0.72 | KIF11 (0.38) | ALDH1A1MAPTSMN1; SMN2TDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470512-B1 | AROMATASE INHIBITOR | ESTRYX PHARMA LTD (GB) | 2018-05-02 | — | — | EP | disclosed |