Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696407 | 0.84 | HSD17B10 (0.50) | CYP1A2CYP3A4HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL20183521 | 0.81 | HSD17B10 (0.53) | CYP1A2CYP3A4HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL20105115 | 0.79 | CLK4 (0.47) | PTPN5CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL6561038 | 0.76 | PTPN5 (0.67) | PTPN5CYP1A2HSD17B10CYP2C19TSHR | |
| SCHEMBL6691557 | 0.74 | FFAR1 (0.54) | ALDH1A1TRPA1FFAR1PPARAHDAC6 | |
| SCHEMBL7435402 | 0.73 | ESR2 (0.56) | PTPN5CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL9532901 | 0.73 | ALDH1A1 (0.52) | CYP1A2CYP3A4HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL9534641 | 0.73 | HDAC1 (0.48) | CYP1A2CYP3A4HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL10061705 | 0.72 | ESR2 (0.54) | PTPN5CYP1A2CYP3A4HSD17B10CYP2C9 | |
| SCHEMBL6692367 | 0.70 | AGER (0.50) | MEN1KMT2ATRPA1FFAR1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | PTPN5 656/4885CYP1A2 15/4885CYP3A4 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.