SCHEMBL2010515

SCHEMBL2010515

COc1ccc(C=Nc2ccc(OC)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.82
PTGS2 P35354 3/20 0.70
PTGS1 P23219 1/20 0.70
CA12 O43570 1/20 0.70
CA2 P00918 1/20 0.70
CA9 Q16790 1/20 0.70
ALDH1A1 P00352 4/20 0.56
ACHE P22303 2/20 0.56
KMT2A Q03164 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
TP53 P04637 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
ALOX15 P16050 1/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12416630 1.00 S100B (0.82) S100BPTGS2PTGS1CA12CA2
SCHEMBL10412841 1.00 S100B (0.82) S100BPTGS2PTGS1CA12CA2
SCHEMBL10733277 1.00 S100B (0.82) S100BPTGS2PTGS1CA12CA2
SCHEMBL10733285 1.00 S100B (0.82) S100BPTGS2PTGS1CA12CA2
SCHEMBL12416663 0.94 S100B (0.74) S100BPTGS2PTGS1CA12CA2
SCHEMBL13038178 0.92 S100B (0.72) S100BPTGS2PTGS1CA12CA2
SCHEMBL269057 0.92 S100B (0.72) S100BPTGS2PTGS1CA12CA2
SCHEMBL16488576 0.92 S100B (0.72) S100BPTGS2PTGS1CA12CA2
SCHEMBL11380636 0.92 S100B (0.72) S100BPTGS2PTGS1CA12CA2
SCHEMBL14129053 0.91 S100B (0.70) S100BPTGS2PTGS1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-11845055-B2 Swellable organically modified silica as nanoreactors APPALACHIAN STATE UNIVERSITY (US) 2023-12-19 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
EP-0284735-B1 DEVICE FOR TAKING BEVERAGES, SUCH AS A STRAW, CUP OR THE LIKE YOSHIYUKI CORPORATION (JP) 1991-04-03 EP disclosed
US-4961972-A APPLYING AND CURING POLYVINYL CHLORIDE PLASTISOL CONTAINING THERMOCHROMIC PARTICLES OF ELECTRON DONORS AND ACCEPTORS AND SOLVENT, ENCAPSULATED BY BILAYER OF POLYMERS MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1990-10-09 US disclosed
US-4851282-A PARTICLES OF POLYMER-ENCAPSULATED CHROMOGENS, LEWIS ACID AND SOLVENT IN A GELLED VINYL CHLORIDE RESIN PLASTISOL; TOUGHNESS MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1989-07-25 US disclosed
EP-0284735-A1 Device for taking beverages, such as a straw, cup or the like YOSHIYUKI CORPORATION (JP) 1988-10-05 EP disclosed
EP-0231030-A2 A thermochromic polyurethane foam and a method for producing the foam MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1987-08-05 EP disclosed
US-4560604-A COATING SURFACE WITH AN ADHESIVE CONTAINING A THERMALLY COLOR-CHANGEABLE PARTICULATE MATERIAL MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1985-12-24 US disclosed
US-4012434-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-03-15 US disclosed
US-4002670-A 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-11 US disclosed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11845055-B2 Swellable organically modified silica as nanoreactors MSN, SORD, OGA S100B 685/4885PTGS2 3420/4885PTGS1 3300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.