Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380636 | 1.00 | S100B (0.72) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL13038178 | 1.00 | S100B (0.72) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL269057 | 1.00 | S100B (0.72) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL10733285 | 0.92 | S100B (0.82) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL2010515 | 0.92 | S100B (0.82) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL12416630 | 0.92 | S100B (0.82) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL10412841 | 0.92 | S100B (0.82) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL10733277 | 0.92 | S100B (0.82) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL12416663 | 0.87 | S100B (0.74) | S100BPTGS2PTGS1CA12CA2 | |
| SCHEMBL255410 | 0.86 | ALDH1A1 (0.74) | S100BPTGS2PTGS1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-11498901-B2 | Hydrogenation of imines with Ru complexes | FIRMENICH SA (CH) | 2022-11-15 | — | — | US | disclosed |
| US-20210371382-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | FIRMENICH SA (CH) | 2021-12-02 | — | — | US | disclosed |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | Universite Paris-Saclay (FR) | 2021-06-15 | — | — | US | disclosed |
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | Universite Paris-Saclay (FR) | 2020-08-13 | — | — | US | disclosed |
| WO-2019063952-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIVERSITE PARIS-SUD (FR) | 2019-04-04 | — | — | WO | disclosed |
| US-9745288-B2 | Compounds and methods for treating cancer by inhibiting the urokinase receptor | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-08-29 | — | — | US | disclosed |
| US-20150051247-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371382-A1 | HYDROGENATION OF IMINES WITH RU COMPLEXES | HRH3, HRH4, HRH2 | S100B 4575/4885PTGS2 2800/4885PTGS1 3646/4885 |
| US-20200255369-A1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | ADH1C, ADH1A, ADH5 | S100B 3594/4885PTGS2 3275/4885PTGS1 3129/4885 |
| US-20150051247-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER BY INHIBITING THE UROKINASE RECEPTOR | PLAUR, PLAU, PLG | S100B 2194/4885PTGS2 387/4885PTGS1 262/4885 |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | ADH1C, PNMT, ADH1A | S100B 3361/4885PTGS2 3092/4885PTGS1 2940/4885 |
| US-11498901-B2 | Hydrogenation of imines with Ru complexes | HRH3, HRH4, HRH2 | S100B 4575/4885PTGS2 2800/4885PTGS1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.