Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254680 | 1.00 | MEN1 (0.38) | MEN1KMT2ASLC6A4SLC6A2OPRL1 | |
| SCHEMBL17254682 | 0.86 | SLC6A4 (0.39) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL20105148 | 0.86 | SLC6A4 (0.39) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL17254699 | 0.83 | CRHBP (0.50) | KMT2AHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20105192 | 0.76 | HTT (0.38) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL17254694 | 0.76 | HTT (0.38) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL20105186 | 0.73 | BRD4 (0.42) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL17254695 | 0.73 | BRD4 (0.42) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL21217885 | 0.73 | SLC6A4 (0.41) | MEN1KMT2ASLC6A4SLC6A2CYP3A4 | |
| SCHEMBL17254853 | 0.72 | CRHBP (0.33) | MEN1KMT2AOPRL1CYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140304-B1 | BENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2018-05-02 | — | — | EP | disclosed |