Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955437 | 1.00 | GPR84 (0.65) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL27613436 | 0.86 | GPR84 (0.49) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL32679648 | 0.83 | HTR2A (0.63) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL6943161 | 0.83 | HTR2A (0.63) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL18967663 | 0.82 | GPR84 (0.65) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL256689 | 0.81 | GPR84 (0.74) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL21912937 | 0.81 | HTR2A (0.65) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL15453266 | 0.80 | HTR2A (0.59) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL20548794 | 0.79 | GPR84 (0.71) | GPR84HTR2AALDH1A1IMPDH2CA2 | |
| SCHEMBL10088110 | 0.79 | GPR84 (0.71) | GPR84HTR2AALDH1A1IMPDH2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072151-A1 | SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF | BAYLOR UNIVERSITY (US) | 2025-04-03 | — | — | WO | disclosed |
| US-10815222-B2 | Compounds for use in the treatment of kinetoplastid infection | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-10-27 | — | — | US | disclosed |
| US-20200095232-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-03-26 | — | — | US | disclosed |
| EP-3558980-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening (IT) | 2019-10-30 | — | — | EP | disclosed |
| US-10351572-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | Magenta Therapeutics Inc. (US) | 2019-07-16 | — | — | US | disclosed |
| WO-2018115275-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | IRBM SCIENCE PARK S.P.A. (IT) | 2018-06-28 | — | — | WO | disclosed |
| US-7964601-B2 | Agonist or antgonist and binders and inversion of agonist | PALATIN TECHNOLOGIES, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-7456184-B2 | Melanocortin receptor-specific compounds | PALATIN TECHNOLOGIES INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080234289-A1 | Melanocortin Receptor-Specific Compounds | PALATIN TECHNOLOGIES, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| EP-1622618-A4 | MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS | PALATIN TECHNOLOGIES INC (US) | 2008-08-27 | — | — | EP | disclosed |
| CN-1816337-A | Naphthalene-containing melanocortin receptor-specific small molecule | PALATIN TECHNOLOGIES INC (US) | 2006-08-09 | — | — | CN | disclosed |
| EP-1622618-A1 | MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS | Palatin Technologies, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004098602-A1 | MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS | PALATIN TECHNOLOGIES, INC. (US) | 2004-11-18 | — | — | WO | disclosed |
| US-20040224957-A1 | Melanocortin receptor-specific compounds | PALATIN TECHNOLOGIES, INC. (US) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815222-B2 | Compounds for use in the treatment of kinetoplastid infection | NISCH, TK2, FDPS | GPR84 1468/4885HTR2A 4718/4885ALDH1A1 1658/4885 |
| US-10351572-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | AHR, ARNT, AIPL1 | GPR84 44/4885HTR2A 124/4885ALDH1A1 86/4885 |
| US-20080234289-A1 | Melanocortin Receptor-Specific Compounds | MC1R, MC3R, MC5R | GPR84 89/4885HTR2A 147/4885ALDH1A1 4174/4885 |
| US-20200095232-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | NISCH, TK2, FDPS | GPR84 1468/4885HTR2A 4718/4885ALDH1A1 1658/4885 |
| US-20040224957-A1 | Melanocortin receptor-specific compounds | MC1R, MC5R, MC3R | GPR84 120/4885HTR2A 95/4885ALDH1A1 3502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.