Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180504 | 0.91 | NPSR1 (0.53) | ALDH1A1MAPTHTTNPSR1POLB | |
| SCHEMBL283988 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTNPSR1POLB | |
| SCHEMBL15316122 | 0.90 | ALDH1A1 (0.61) | ALDH1A1MAPTHTTNPSR1POLB | |
| Hydrochloric Acid SCHEMBL28554078 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTNPSR1POLB | |
| Hydrochloric Acid SCHEMBL451487 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTNPSR1POLB | |
| SCHEMBL28517649 | 0.87 | ALDH1A1 (0.65) | ALDH1A1MAPTHTTNPSR1POLB | |
| Bromide SCHEMBL1608735 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTNPSR1POLB | |
| SCHEMBL18027642 | 0.84 | CRHR1 (0.49) | ALDH1A1MAPTHTTNPSR1POLB | |
| SCHEMBL2366412 | 0.84 | ADRB1 (0.50) | ALDH1A1MAPTHTTNPSR1POLB | |
| SCHEMBL27892747 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTHTTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080917-A1 | FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |