Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 9/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957514 | 1.00 | TP53 (0.52) | TP53TDP1PDE10ACA2LPL | |
| SCHEMBL792416 | 0.81 | TSHR (0.48) | CA2LPLLIPGENPP2KDM4E | |
| SCHEMBL29817989 | 0.80 | CA2 (0.52) | CA2LPLLIPGENPP2KDM4E | |
| SCHEMBL40868 | 0.80 | CA2 (0.52) | CA2LPLLIPGENPP2KDM4E | |
| SCHEMBL16426121 | 0.78 | ENPP2 (0.46) | CA2LPLLIPGENPP2KDM4E | |
| SCHEMBL3928671 | 0.78 | CA2 (0.50) | CA2LPLLIPGENPP2KDM4E | |
| SCHEMBL1277359 | 0.77 | ENPP2 (0.50) | CA2LPLLIPGENPP2KDM4E | |
| SCHEMBL5839148 | 0.74 | CA2 (0.46) | CA2LPLLIPGENPP2ALDH1A1 | |
| SCHEMBL177405 | 0.74 | TTR (0.50) | CA2LPLLIPGENPP2CA1 | |
| SCHEMBL3194289 | 0.74 | ALDH1A1 (0.50) | TDP1CA2LPLLIPGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240200-A | Low-dielectric fluorine-containing polyarylether resin and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-06-25 | — | — | CN | claimed |
| CN-116731315-B | Boron-containing phthalonitrile resin and preparation method and application thereof | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | claimed |
| CN-116731315-A | Boron-containing phthalonitrile resin and preparation method and application thereof | 中国科学院化学研究所 | 2023-09-12 | — | — | CN | claimed |
| CN-115491252-B | Low-foam wetting agent for precious stone cutting and preparation method thereof | 江苏四新界面剂科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-115491252-A | Low-foam wetting agent for cutting jewels and preparation method thereof | 江苏四新界面剂科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-118240200-A | Low-dielectric fluorine-containing polyarylether resin and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-06-25 | — | — | CN | disclosed |
| CN-116731315-B | Boron-containing phthalonitrile resin and preparation method and application thereof | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-116731315-A | Boron-containing phthalonitrile resin and preparation method and application thereof | 中国科学院化学研究所 | 2023-09-12 | — | — | CN | disclosed |
| CN-115491252-B | Low-foam wetting agent for precious stone cutting and preparation method thereof | 江苏四新界面剂科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115491252-A | Low-foam wetting agent for cutting jewels and preparation method thereof | 江苏四新界面剂科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| US-11248170-B2 | Polymerizable compound and application thereof | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2022-02-15 | — | — | US | disclosed |
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | disclosed |
| US-20100120775-A1 | Farnesoid X Receptor Agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120775-A1 | Farnesoid X Receptor Agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2079307-A2 | FARNESOID X RECEPTOR AGONISTS | SmithKline Beecham Corporation (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008051942-A2 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008051942-A2 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-02 | — | — | WO | disclosed |
| US-20080096921-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096921-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096921-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120775-A1 | Farnesoid X Receptor Agonists | NR1H4, NR1H3, NR1H2 | TP53 4565/4885TDP1 4574/4885PDE10A 876/4885 |
| US-20080096921-A1 | FARNESOID X RECEPTOR AGONISTS | NR1H4, NR1H3, NR1H2 | TP53 4565/4885TDP1 4574/4885PDE10A 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.