Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17393833 | 0.78 | PIK3CD (0.35) | PTGS2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL16014764 | 0.76 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL23174400 | 0.76 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL17402844 | 0.75 | — | — | |
| SCHEMBL29377271 | 0.75 | L3MBTL1 (0.62) | PTGS2CCR2L3MBTL1PIK3CDPIK3CA | |
| SCHEMBL239424 | 0.75 | L3MBTL1 (0.62) | PTGS2CCR2L3MBTL1PIK3CDPIK3CA | |
| Ammonia Solution, Strong SCHEMBL17394086 | 0.74 | PTGS2 (0.34) | PTGS2CCR2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL12560662 | 0.71 | CCR2 (0.68) | CCR2L3MBTL1 | |
| SCHEMBL30431062 | 0.71 | L3MBTL1 (0.62) | L3MBTL1 | |
| SCHEMBL282188 | 0.71 | L3MBTL1 (0.62) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |