SCHEMBL29377271

SCHEMBL29377271

CS(=O)(=O)c1ccc(N)cc1F

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
CCR2 P41597 2/20 0.42
GRM4 Q14833 1/20 0.39
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37
PIK3CG P48736 1/20 0.37
GPR119 Q8TDV5 1/20 0.35
HSD11B1 P28845 1/20 0.35
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239424 1.00 L3MBTL1 (0.62) L3MBTL1CCR2GRM4PIK3CDPIK3CA
SCHEMBL3451784 0.83 L3MBTL1 (0.57) L3MBTL1CCR2GRM4ALOX5APFEN1
SCHEMBL18545803 0.83 L3MBTL1 (0.45) L3MBTL1CCR2HSD11B1ALDH1A1CYP3A4
SCHEMBL31618993 0.81 L3MBTL1 (0.44) L3MBTL1PIK3CBCA12CA1CA2
SCHEMBL1575759 0.81 CA2 (0.44) L3MBTL1CA12CA1CA2CA4
SCHEMBL31618994 0.81 L3MBTL1 (0.44) L3MBTL1PIK3CBCA12CA1CA2
SCHEMBL30049401 0.81 CA2 (0.44) L3MBTL1CA12CA1CA2CA4
SCHEMBL20226640 0.80 GAA (0.47) L3MBTL1CCR2HSD11B1ALOX5APFEN1
SCHEMBL3425338 0.79 RAPGEF4 (0.47) L3MBTL1CA2ALDH1A1CYP3A4THRB
SCHEMBL20149266 0.79 L3MBTL1 (0.43) L3MBTL1HSD11B1ALOX5APFEN1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527763-B2 Pyrrole amide compound and use thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2026-01-20 US disclosed
CN-111196804-B TGF-beta R1 inhibitors and uses thereof 南京圣和药业股份有限公司 2023-11-07 CN disclosed
WO-2023043630-A1 COMPOUNDS HAVING N-ARYLPYRIMIDIN-2-AMINE DERIVATIVES AS THERAPEUTIC AGENTS LOMOND THERAPEUTICS, INC. (US) 2023-03-23 WO disclosed
US-20220211665-A1 PYRROLE AMIDE COMPOUND AND USE THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-07-07 US disclosed
CN-114702427-A Pyrrole amide compound and application thereof 年衍药业(珠海)有限公司 2022-07-05 CN disclosed
CN-109415381-B Thiazolopyridine derivatives as GPR119 agonists 人类制药有限公司 2022-03-25 CN disclosed
CN-112707854-B Pyrrole amide compound and application thereof 年衍药业(珠海)有限公司 2022-03-15 CN disclosed
EP-3950674-A1 PYRROLE AMIDE COMPOUND AND USE THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527763-B2 Pyrrole amide compound and use thereof NR3C2, AVPR2, MC2R L3MBTL1 4691/4885CCR2 897/4885GRM4 1404/4885
US-20220211665-A1 PYRROLE AMIDE COMPOUND AND USE THEREOF MC2R, NR3C2, AVPR2 L3MBTL1 4882/4885CCR2 1260/4885GRM4 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.