Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316007 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EGRNSORT1 | |
| SCHEMBL17076723 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EGRNSORT1 | |
| Hydrochloric Acid SCHEMBL31467467 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAAKDM4EGRNSORT1 | |
| SCHEMBL20441139 | 0.79 | KDM4E (0.42) | ALDH1A1GAAKDM4EGRNSORT1 | |
| SCHEMBL20113280 | 0.79 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4EGRNSORT1 | |
| SCHEMBL19357273 | 0.75 | LMNA (0.49) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL16450837 | 0.75 | KDM4E (0.40) | KDM4EGRNSORT1SMN1; SMN2MEN1 | |
| SCHEMBL12011418 | 0.75 | MEN1 (0.42) | ALDH1A1KDM4EGRNSORT1SMN1; SMN2 | |
| SCHEMBL334463 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1GAAKDM4EGRNSORT1 | |
| SCHEMBL18719698 | 0.74 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4EGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | Prosetta Antiviral ,Inc. | 2018-05-03 | — | — | US | disclosed |
| US-20180118679-A1 | N-Methyl Pyrazoles | Prosetta Antiviral ,Inc. | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | ZC3HAV1, MAVS, NNMT | ALDH1A1 3967/4885GAA 1647/4885KDM4E 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.