Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109193 | 0.73 | FAAH (0.43) | FAAHPTGS2GRM7HPGDPTGS1 | |
| SCHEMBL20109150 | 0.70 | CYP2D6 (0.36) | FAAHPTGS2GRM7HPGDALDH1A1 | |
| SCHEMBL10628842 | 0.68 | PTGS2 (0.47) | FAAHPTGS2HPGDPTGS1ALDH1A1 | |
| SCHEMBL13177031 | 0.67 | PTGS2 (0.45) | PTGS2HPGDPTGS1ALDH1A1CYP3A4 | |
| SCHEMBL16168604 | 0.67 | PTGS2 (0.45) | PTGS2HPGDPTGS1ALDH1A1CYP3A4 | |
| SCHEMBL13176481 | 0.67 | PTGS2 (0.45) | PTGS2HPGDPTGS1ALDH1A1CYP3A4 | |
| SCHEMBL4813777 | 0.65 | PTGS2 (0.43) | FAAHPTGS2HPGDALDH1A1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL11508344 | 0.65 | PTGS2 (0.43) | FAAHPTGS2HPGDALDH1A1CYP3A4 | |
| SCHEMBL2163297 | 0.65 | HPGD (0.47) | PTGS2HPGDALDH1A1CYP3A4TSHR | |
| SCHEMBL348322 | 0.65 | HPGD (0.52) | FAAHPTGS2GRM7HPGDPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | FAAH 3458/4885PTGS2 1929/4885GRM7 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.