Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159834 | 0.92 | RELA (0.42) | PTGS2KDM1AMAPK1NPC1POLB | |
| SCHEMBL20109433 | 0.88 | APP (0.45) | PTGS2HPGDAPPMAPK1NPC1 | |
| SCHEMBL18157326 | 0.86 | NPC1 (0.36) | HPGDAPPMAPK1NPC1POLB | |
| SCHEMBL13237078 | 0.86 | APP (0.40) | HPGDAPPPOLBRAB9AALDH1A1 | |
| SCHEMBL18157318 | 0.85 | PTGS2 (0.41) | PTGS2HPGDKDM1AAPPMAPK1 | |
| SCHEMBL13237082 | 0.85 | APP (0.42) | HPGDAPPPOLBRAB9AALDH1A1 | |
| SCHEMBL14537277 | 0.81 | RELA (0.44) | PTGS2HPGDAPPMAPK1NPC1 | |
| SCHEMBL2153287 | 0.81 | RELA (0.44) | PTGS2HPGDAPPMAPK1NPC1 | |
| SCHEMBL14537271 | 0.81 | RELA (0.44) | PTGS2HPGDAPPMAPK1NPC1 | |
| SCHEMBL11976748 | 0.80 | ALDH1A1 (0.38) | PTGS2HPGDAPPMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663447-B2 | Asymmetric butadiene-based charge transport compound, electrophotographic photoreceptor containing same, and image forming apparatus | S-PRINTING SOLUTION CO., LTD. (KR) | 2017-05-30 | — | — | US | disclosed |
| US-20160304437-A1 | ASYMMETRIC BUTADIENE-BASED CHARGE TRANSPORT COMPOUND, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME, AND IMAGE FORMING APPARATUS | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304437-A1 | ASYMMETRIC BUTADIENE-BASED CHARGE TRANSPORT COMPOUND, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME, AND IMAGE FORMING APPARATUS | ALDH1A2, USE1, SLC9A1 | PTGS2 2881/4885HPGD 1497/4885KDM1A 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.