Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | PCNA | P12004 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015428 | 0.87 | PLK1 (0.40) | MTNR1AMPORAB9A | |
| SCHEMBL8027585 | 0.81 | MPO (0.50) | MTNR1AMTNR1BMPORAB9ACCNC | |
| SCHEMBL20109375 | 0.75 | FFAR1 (0.46) | MTNR1APCNAMTNR1BRAB9AHDAC1 | |
| SCHEMBL12851277 | 0.74 | TAAR1 (0.55) | MTNR1AMTNR1BRAB9AACKR3 | |
| SCHEMBL14234026 | 0.73 | HPGD (0.46) | MPO | |
| SCHEMBL8055086 | 0.73 | BACE1 (0.39) | RAB9A | |
| SCHEMBL7941769 | 0.72 | POLB (0.54) | RAB9A | |
| SCHEMBL8979678 | 0.72 | MPO (0.53) | MTNR1AMPORAB9AHDAC1FFAR1 | |
| SCHEMBL7933157 | 0.72 | MAPT (0.52) | RAB9A | |
| SCHEMBL14387746 | 0.71 | HDAC1 (0.53) | PCNAHDAC1HDAC8HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534152-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-02 | — | — | EP | disclosed |