Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20084193 | 0.88 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL25075136 | 0.83 | ACHE (0.36) | OPRK1 | |
| SCHEMBL23103611 | 0.80 | — | — | |
| SCHEMBL25075205 | 0.78 | ACHE (0.42) | OPRK1 | |
| SCHEMBL25089948 | 0.78 | — | — | |
| SCHEMBL22435969 | 0.75 | — | — | |
| SCHEMBL20097471 | 0.75 | — | — | |
| SCHEMBL8235125 | 0.74 | NCF1 (0.44) | OPRK1 | |
| SCHEMBL22020557 | 0.74 | NCF1 (0.44) | OPRK1 | |
| SCHEMBL23645702 | 0.74 | NCF1 (0.44) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534152-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-02 | — | — | EP | disclosed |