Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075136 | 0.90 | ACHE (0.36) | ACHEOPRK1 | |
| SCHEMBL20084193 | 0.89 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL10092708 | 0.85 | ACHE (0.50) | ACHECHRM5ADRA2COPRK1 | |
| SCHEMBL20109930 | 0.78 | OPRK1 (0.32) | OPRK1 | |
| SCHEMBL22541172 | 0.75 | CHRM5 (0.36) | ACHECHRM5ADRA2C | |
| SCHEMBL23103580 | 0.75 | THRB (0.42) | ACHECHRM5ADRA2C | |
| SCHEMBL25075002 | 0.74 | ACHE (0.39) | ACHECHRM5ADRA2COPRK1 | |
| SCHEMBL25074996 | 0.73 | ACHE (0.36) | ACHECHRM5ADRA2COPRK1 | |
| SCHEMBL24746583 | 0.73 | NCF1 (0.42) | ACHECHRM5ADRA2C | |
| SCHEMBL25089948 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023537-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BRUTON'S TYROSINE KINASE | ENDOTARGET INC. (US) | 2023-02-23 | — | — | WO | disclosed |