Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153354 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNACYP1A2CYP2C19SIGMAR1 | |
| SCHEMBL3271284 | 0.81 | SIGMAR1 (0.48) | ALDH1A1LMNACYP1A2CYP2C19SIGMAR1 | |
| SCHEMBL9911525 | 0.81 | KMT2A (0.59) | ALDH1A1LMNACYP1A2CYP2C19ALOX15 | |
| SCHEMBL20850576 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNACYP1A2CYP2C19ALOX15 | |
| SCHEMBL12674550 | 0.77 | KMT2A (0.55) | ALDH1A1LMNACYP1A2CYP2C19ALOX15 | |
| SCHEMBL12667380 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNACYP1A2CYP2C19SIGMAR1 | |
| SCHEMBL19080482 | 0.76 | PRSS1 (0.52) | LMNAITGB3 | |
| Methyl Alcohol SCHEMBL29261100 | 0.75 | SIGMAR1 (0.61) | ALDH1A1LMNASIGMAR1SMN1; SMN2POLB | |
| SCHEMBL9781281 | 0.75 | SLC6A2 (0.48) | ALDH1A1LMNASIGMAR1ALOX15POLB | |
| SCHEMBL143708 | 0.74 | SIGMAR1 (0.65) | SIGMAR1SMN1; SMN2POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640466-B2 | Anthracene based compounds and their uses | UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) | 2020-05-05 | — | — | US | disclosed |
| US-20180118685-A1 | ANTHRACENE BASED COMPOUNDS AND THEIR USES | UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) | 2018-05-03 | — | — | US | disclosed |
| US-20180118685-A1 | ANTHRACENE BASED COMPOUNDS AND THEIR USES | UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION (GB) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118685-A1 | ANTHRACENE BASED COMPOUNDS AND THEIR USES | CYP2D6, CYP3A43, ACMSD | ALDH1A1 1242/4885LMNA 823/4885CYP1A2 11/4885 |
| US-10640466-B2 | Anthracene based compounds and their uses | CYP2D6, CYP3A43, ACMSD | ALDH1A1 1242/4885LMNA 823/4885CYP1A2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.