SCHEMBL20110419

SCHEMBL20110419

O=S(=O)(Nc1ccccc1-c1nc2ccccc2o1)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.73
KMT2A Q03164 5/20 0.73
PTPN1 P18031 12/20 0.64
PTPN5 P54829 11/20 0.64
PTPN2 P17706 11/20 0.64
MAPT P10636 4/20 0.64
HPGD P15428 2/20 0.64
HSD17B10 Q99714 1/20 0.64
ALDH1A1 P00352 2/20 0.62
GAA P10253 1/20 0.62
LMNA P02545 1/20 0.58
KDM4E B2RXH2 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
HSPD1 P10809 7/20 0.53
HSPE1 P61604 7/20 0.53
PTGS2 P35354 1/20 0.52
STK33 Q9BYT3 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6862724 0.90 PTPN1 (0.67) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL5975597 0.84 KMT2A (1.00) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL23533659 0.84 MEN1 (0.70) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL13490141 0.83 PTGS2 (0.58) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL10819490 0.79 KMT2A (0.88) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL9528544 0.78 KMT2A (0.86) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL8927385 0.78 PTPN1 (0.71) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL5975754 0.77 KMT2A (0.84) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL924320 0.77 MAPT (1.00) MEN1KMT2APTPN1PTPN5PTPN2
SCHEMBL9528246 0.77 MAPT (1.00) MEN1KMT2APTPN1PTPN5PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005827-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2021-01-07 US disclosed
US-10790454-B2 N and P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2020-09-29 US disclosed
US-20180123050-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2018-05-03 US disclosed
US-20180123050-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10790454-B2 N and P active materials for organic photoelectric conversion layers in organic photodiodes L1CAM, PNN, JUP MEN1 2212/4885KMT2A 2728/4885PTPN1 911/4885
US-20180123050-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES L1CAM, PNN, JUP MEN1 2212/4885KMT2A 2728/4885PTPN1 911/4885
US-20210005827-A1 N AND P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES L1CAM, PNN, JUP MEN1 2212/4885KMT2A 2728/4885PTPN1 911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.