Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMG3 | Q9BT73 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20110957 | 0.75 | CYP3A4 (0.32) | — | |
| SCHEMBL12157050 | 0.70 | SMN1; SMN2 (0.46) | PSMG3 | |
| SCHEMBL12157049 | 0.68 | PSMG3 (0.49) | PSMG3 | |
| SCHEMBL15656087 | 0.66 | ALDH1A1 (0.37) | — | |
| SCHEMBL9752570 | 0.65 | CYP3A4 (0.44) | KCNA3PTPN1 | |
| SCHEMBL11121530 | 0.65 | CYP3A4 (0.44) | KCNA3PTPN1 | |
| SCHEMBL684711 | 0.64 | KCNA3 (0.49) | PSMG3IMPDH2KCNA3 | |
| SCHEMBL14299196 | 0.64 | TSHR (0.32) | — | |
| SCHEMBL1003356 | 0.63 | POLB (0.41) | PSMG3PTPN1 | |
| SCHEMBL10474965 | 0.63 | PSMG3 (0.51) | PSMG3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | CBS, TST, STS | PSMG3 1826/4885IMPDH2 2522/4885KCNA3 4634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.