Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729284 | 0.97 | KIF11 (0.32) | TSHRPDE2AMAOBKIF11 | |
| SCHEMBL7733408 | 0.92 | PPARG (0.32) | TSHRPPARGPPARDPPARAPDE2A | |
| SCHEMBL7722571 | 0.92 | PPARD (0.39) | TSHREPHX2NR1H4PPARGPPARD | |
| SCHEMBL7722827 | 0.91 | DAO (0.36) | TSHREPHX2NR1H4PPARGPPARD | |
| SCHEMBL7730994 | 0.90 | FFAR1 (0.33) | TSHREPHX2NR1H4EPHX1KIF11 | |
| SCHEMBL7735261 | 0.89 | MAOB (0.36) | PPARGPPARDPPARAMAOBALDH1A1 | |
| SCHEMBL7729688 | 0.88 | TSHR (0.36) | TSHREPHX2NR1H4PDE2AMAOB | |
| SCHEMBL7730657 | 0.87 | PSEN1 (0.37) | PPARGPPARDPPARAMAOB | |
| SCHEMBL7732825 | 0.86 | TAAR1 (0.37) | PPARGPDE2AMAOB | |
| SCHEMBL7722573 | 0.85 | THRB (0.39) | PPARGPPARDPPARAALDH1A1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |