SCHEMBL20111248

SCHEMBL20111248

CCOc1ccc2c(c1F)-c1c-2cc(CCC2CCCCC2)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
QRFPR Q96P65 1/20 0.36
HPGD P15428 5/20 0.36
APOBEC3G Q9HC16 2/20 0.34
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
BRD4 O60885 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
NPBWR1 P48145 1/20 0.33
MCHR1 Q99705 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CEL P19835 1/20 0.33
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111710 0.94 HPGD (0.33) QRFPRHPGDAPOBEC3GALDH1A1TSHR
SCHEMBL20117586 0.91 ALDH1A1 (0.32) QRFPRALDH1A1KDM1A
SCHEMBL20102468 0.89 HPGD (0.30) QRFPRHPGDKDM1A
SCHEMBL20111512 0.88 CYP19A1 (0.34) QRFPRHPGD
SCHEMBL20111639 0.87 CCNT1 (0.32) ALDH1A1
SCHEMBL20102469 0.87
SCHEMBL20102549 0.86
SCHEMBL21609934 0.85 CEL (0.41) QRFPRHPGDAPOBEC3GALDH1A1TSHR
SCHEMBL20117659 0.84 FGFR2 (0.30)
SCHEMBL20102404 0.82 CTSL (0.39) ALDH1A1MAPTKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S QRFPR 2307/4885HPGD 4744/4885APOBEC3G 942/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S QRFPR 2307/4885HPGD 4744/4885APOBEC3G 942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.