SCHEMBL20111708

SCHEMBL20111708

CCCc1cc2c(c(F)c1F)-c1c-2ccc(C#Cc2ccc(C)cc2)c1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20102532 0.86 HSD17B10 (0.39) FFAR1
SCHEMBL20111611 0.81 PTGS2 (0.34) FFAR1
SCHEMBL20117677 0.81 CA12 (0.33) FFAR1KCNH2
SCHEMBL7859815 0.81 FFAR1 (0.36) FFAR1KCNH2
SCHEMBL7858993 0.76 FFAR1 (0.46) FFAR1
SCHEMBL20111315 0.75 CTSL (0.34) FFAR1
SCHEMBL7858818 0.73 KCNH2 (0.37) FFAR1KCNH2
SCHEMBL9512412 0.73 FFAR1 (0.41) FFAR1
SCHEMBL9512352 0.73 FFAR1 (0.41) FFAR1
SCHEMBL20102397 0.72 CTSL (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S FFAR1 536/4885KCNH2 1137/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S FFAR1 536/4885KCNH2 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.