Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24130544 | 0.81 | ALDH1A1 (0.39) | ALDH1A1EPHX2LMNASLC15A2RECQL | |
| SCHEMBL13311531 | 0.79 | CYP2D6 (0.50) | ALDH1A1EPHX2LMNASLC15A2HPGD | |
| SCHEMBL13779167 | 0.77 | MTNR1A (0.39) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL13918157 | 0.77 | MTNR1A (0.39) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL13918161 | 0.77 | MTNR1A (0.39) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10136021 | 0.74 | ALDH1A1 (0.40) | ALDH1A1EPHX2LMNASLC15A2HPGD | |
| SCHEMBL12898838 | 0.71 | CYP2C19 (0.34) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL14725897 | 0.71 | ALDH1A1 (0.40) | ALDH1A1EPHX2LMNASLC15A2HPGD | |
| SCHEMBL25076213 | 0.70 | ADH1B (0.38) | LMNA | |
| SCHEMBL12707688 | 0.70 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081530-A1 | COMPOSITIONS AND METHODS FOR TREATING EZH2-MEDIATED CANCER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-05-03 | — | — | WO | disclosed |