Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815243 | 0.89 | PTPN1 (0.36) | ALDH1A1LMNACYP2C19HIF1AASAH1 | |
| SCHEMBL20149852 | 0.89 | PTPN1 (0.36) | ALDH1A1LMNACYP2C19HIF1AASAH1 | |
| SCHEMBL2414889 | 0.83 | LMNA (0.39) | ALDH1A1LMNACYP2C19HIF1AEGFR | |
| SCHEMBL22814737 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNASLC15A2ASAH1EPHX2 | |
| SCHEMBL23790740 | 0.82 | PHF8 (0.43) | ALDH1A1LMNAPTPN1KDM4EFAAH | |
| SCHEMBL12122298 | 0.82 | CASP2 (0.44) | ALDH1A1LMNAASAH1DRD3SLC6A3 | |
| SCHEMBL12214348 | 0.81 | NAAA (0.39) | ALDH1A1LMNACYP2C19HIF1AEGFR | |
| SCHEMBL27108993 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNACYP2C19SLC15A2ASAH1 | |
| SCHEMBL19431140 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNACYP2C19HIF1AEPHX2 | |
| SCHEMBL12214453 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNACYP2C19HIF1AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257827-A1 | CONJUGATES AND PREPARATION AND USE THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-2382199-B1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | GFBIOCHEMICALS LTD (MT) | 2016-11-16 | — | — | EP | disclosed |
| US-20150175568-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | GFBIOCHEMICALS LIMITED (MT) | 2015-06-25 | — | — | US | disclosed |
| US-8969559-B2 | Ketal amide compounds, methods of making, and applications | SEGETIS, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130053564-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | SEGETIS, INC. (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053564-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | KAT6A, KAT6B, KAT5 | ALDH1A1 983/4885LMNA 2934/4885CYP2C19 1437/4885 |
| US-20150175568-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | KAT6A, KAT6B, KAT5 | ALDH1A1 983/4885LMNA 2934/4885CYP2C19 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.