SCHEMBL20111910

SCHEMBL20111910

CC1=CC(C)N(S(=O)(=O)C2CN(C(C)C)C2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111631 0.90 PIK3CA (0.32)
SCHEMBL21732948 0.82
SCHEMBL20111728 0.72 LMNA (0.35) LMNAGAA
SCHEMBL20111907 0.71 L3MBTL1 (0.31)
SCHEMBL21732947 0.68
SCHEMBL20111909 0.66 SMYD3 (0.30)
SCHEMBL20111730 0.65 SMYD3 (0.30)
SCHEMBL20111633 0.64 PIK3CA (0.32)
SCHEMBL21732883 0.64
SCHEMBL20111630 0.63 JAK2 (0.33) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018078360-A1 MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY E-THERAPEUTICS PLC (GB) 2018-05-03 WO disclosed