Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111630 | 0.90 | JAK2 (0.33) | LMNAGAA | |
| SCHEMBL21732946 | 0.81 | LMNA (0.30) | LMNAGAA | |
| SCHEMBL17888259 | 0.80 | JAK1 (0.36) | LMNATHRBL3MBTL1 | |
| SCHEMBL17888199 | 0.78 | CHRM4 (0.33) | LMNATHRBL3MBTL1 | |
| SCHEMBL17888250 | 0.78 | CHRM4 (0.35) | LMNATHRBL3MBTL1 | |
| SCHEMBL17888204 | 0.74 | NAMPT (0.44) | LMNAGAATHRBL3MBTL1 | |
| SCHEMBL20111910 | 0.72 | LMNA (0.31) | LMNAGAA | |
| SCHEMBL20111907 | 0.72 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL12286066 | 0.71 | TDO2 (0.43) | LMNATHRBL3MBTL1 | |
| SCHEMBL1109602 | 0.70 | LMNA (0.41) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |