Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165409 | 0.92 | GPR174 (0.40) | ELANEGPR174KMT2AMAPTMAPK1 | |
| SCHEMBL9607858 | 0.89 | ELANE (0.51) | ELANEKMT2AATMMAPTKDM4E | |
| SCHEMBL21655391 | 0.88 | KMT2A (0.40) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL22001782 | 0.87 | ELANE (0.50) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL19882306 | 0.87 | ELANE (0.50) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL17546961 | 0.87 | ELANE (0.50) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL20112832 | 0.87 | MAPT (0.42) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL22023572 | 0.87 | GPR174 (0.40) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL18509891 | 0.86 | GPR174 (0.40) | ELANEGPR174KMT2AATMMAPT | |
| SCHEMBL20312224 | 0.84 | ELANE (0.43) | ELANEGPR174KMT2AATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550327-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2020-02-04 | — | — | US | disclosed |
| US-10400169-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-09-03 | — | — | US | disclosed |
| EP-3260518-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-3257916-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | ELANE 3896/4885GPR174 3472/4885KMT2A 2248/4885 |
| US-10400169-B2 | Liquid-crystalline medium | VIM, COL2A1, COL1A1 | ELANE 3896/4885GPR174 3472/4885KMT2A 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.