Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922336 | 0.90 | F2 (0.41) | F2LIMK1TRPA1MAPTCTSD | |
| SCHEMBL19669165 | 0.82 | F2 (0.40) | F2MAPTALDH1A1CTSDACHE | |
| SCHEMBL2128482 | 0.80 | KDM6B (0.47) | F2HDAC3HDAC1HDAC2LIMK1 | |
| SCHEMBL2352696 | 0.78 | NAAA (0.50) | F2HDAC3HDAC1HDAC2LIMK1 | |
| SCHEMBL20626527 | 0.77 | F2 (0.39) | F2LIMK1TRPA1MAPTCTSD | |
| SCHEMBL25383583 | 0.77 | NAAA (0.53) | HDAC3HDAC1HDAC2MAPTALDH1A1 | |
| SCHEMBL11470387 | 0.77 | NAAA (0.53) | HDAC3HDAC1HDAC2MAPTALDH1A1 | |
| SCHEMBL11477556 | 0.77 | NAAA (0.53) | HDAC3HDAC1HDAC2MAPTALDH1A1 | |
| SCHEMBL2262258 | 0.77 | NAAA (0.53) | HDAC3HDAC1HDAC2MAPTALDH1A1 | |
| SCHEMBL11470551 | 0.77 | NAAA (0.53) | HDAC3HDAC1HDAC2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | F2 203/4885HDAC3 1354/4885HDAC1 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.