SCHEMBL19669165

SCHEMBL19669165

CC(C)(C)CCCNc1ccncc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.40
▸ MAPT P10636 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ CTSD P07339 1/20 0.38
▸ FDPS P14324 1/20 0.36
▸ ADRA2B P18089 1/20 0.36
▸ KCNH2 Q12809 1/20 0.36
▸ GRIN2B Q13224 1/20 0.36
▸ ACHE P22303 4/20 0.35
▸ GFER P55789 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2128107 0.88 F2 (0.41) F2MAPTCTSDFDPSADRA2B
SCHEMBL20112844 0.82 F2 (0.39) F2MAPTALDH1A1CTSDACHE
SCHEMBL5335241 0.78 KCNH3 (0.41) F2MAPTALDH1A1
SCHEMBL2128482 0.78 KDM6B (0.47) F2MAPTALDH1A1CTSD
SCHEMBL10274903 0.76 MAPT (0.46) F2MAPTALDH1A1CTSDFDPS
SCHEMBL2352696 0.76 NAAA (0.50) F2MAPTALDH1A1CTSDACHE
SCHEMBL20626527 0.76 F2 (0.39) F2MAPTCTSDFDPSADRA2B
SCHEMBL19468970 0.75 CTSD (0.44) F2CTSDFDPSADRA2B
SCHEMBL26941343 0.75 ADRA2B (0.36) F2MAPTALDH1A1ADRA2BKCNH2
SCHEMBL25383583 0.74 NAAA (0.53) MAPTALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118754-A1 COMPOUNDS RESPIVERT LTD. (GB) 2018-05-03 — — US disclosed
US-9834560-B2 Compounds RESPIVERT LTD. (GB) 2017-12-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118754-A1 COMPOUNDS LTC4S, CYP11B2, LTB4R2 F2 203/4885MAPT 2191/4885ALDH1A1 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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