Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23330997 | 0.88 | DPP7 (0.38) | L3MBTL1ALDH1A1CASP2NAAAMEN1 | |
| SCHEMBL254806 | 0.86 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1CASP2NAAAMEN1 | |
| SCHEMBL868573 | 0.83 | OTC (0.50) | DPP7 | |
| SCHEMBL868574 | 0.83 | OTC (0.50) | DPP7 | |
| SCHEMBL23330799 | 0.80 | ALB (0.41) | L3MBTL1ALDH1A1CASP2NAAAMEN1 | |
| SCHEMBL23771992 | 0.80 | ALB (0.36) | L3MBTL1ALDH1A1CASP2NAAAMEN1 | |
| SCHEMBL16691386 | 0.80 | CASP2 (0.61) | ALDH1A1CASP2TP53NAAAMEN1 | |
| SCHEMBL23330800 | 0.80 | ALB (0.42) | L3MBTL1ALDH1A1CASP2NAAAMEN1 | |
| SCHEMBL20751442 | 0.79 | SLC6A5 (0.48) | ALDH1A1CASP2TP53NAAAMEN1 | |
| SCHEMBL14682756 | 0.79 | L3MBTL1 (0.36) | L3MBTL1CASP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438174-B1 | METHOD FOR INCORPORATING ALIPHATIC AMINO ACIDS COMPRISING ALKYNE, AZIDE OR ALIPHATIC KETONE FUNCTIONAL GROUPS USING APPROPRIATE tRNA/tRNA SYNTHASE PAIRS | MEDICAL RES COUNCIL (GB) | 2018-05-02 | — | — | EP | disclosed |