SCHEMBL254806

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20113003	0.86	L3MBTL1 (0.40)	L3MBTL1CASP2NAAAALDH1A1EPHX2
	SCHEMBL10345306	0.83	NAMPT (0.52)	CASP2NAAAALDH1A1NAMPTEPHX2
	SCHEMBL10660707	0.83	NAMPT (0.52)	CASP2NAAAALDH1A1NAMPTEPHX2
	SCHEMBL22851659	0.83	ALDH1A1 (0.53)	CASP2NAAAALDH1A1NAMPTLMNA
	SCHEMBL16689691	0.83	ALDH1A1 (0.53)	CASP2NAAAALDH1A1NAMPTLMNA
	SCHEMBL24818366	0.83	NAMPT (0.52)	CASP2NAAAALDH1A1NAMPTEPHX2
	SCHEMBL18768756	0.83	ALDH1A1 (0.53)	CASP2NAAAALDH1A1NAMPTLMNA
	SCHEMBL10345059	0.83	NAMPT (0.52)	CASP2NAAAALDH1A1NAMPTEPHX2
	SCHEMBL18313728	0.82	ALDH1A1 (0.52)	L3MBTL1CASP2NAAAALDH1A1NAMPT
	SCHEMBL10051016	0.81	CASP2 (0.67)	L3MBTL1CASP2NAAAEPHX2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.