Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.65 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112961 | 0.94 | GRM7 (0.58) | GRM7P2RX7POLBMC4RF2 | |
| SCHEMBL20113080 | 0.86 | GRM7 (0.74) | GRM7P2RX7MEN1KMT2A | |
| SCHEMBL20112967 | 0.83 | GRM7 (0.58) | GRM7P2RX7POLBHSP90AA1HSP90AB1 | |
| SCHEMBL20113020 | 0.83 | GRM7 (0.68) | GRM7KMT2A | |
| SCHEMBL20113019 | 0.83 | GRM7 (0.68) | GRM7HSP90AA1HSP90AB1KMT2A | |
| SCHEMBL20113106 | 0.83 | GRM7 (0.74) | GRM7MEN1KMT2A | |
| SCHEMBL20113104 | 0.83 | GRM7 (0.74) | GRM7MEN1KMT2A | |
| SCHEMBL20112965 | 0.80 | GRM7 (0.57) | GRM7P2RX7MEN1KMT2A | |
| SCHEMBL20112956 | 0.80 | GRM7 (0.62) | GRM7P2RX7HSP90AA1HSP90AB1 | |
| SCHEMBL20112958 | 0.80 | GRM7 (0.59) | GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |