Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667065 | 0.98 | PON1 (0.50) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| Water SCHEMBL31529728 | 0.96 | PON1 (0.49) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| Iodide SCHEMBL2195237 | 0.96 | PON1 (0.49) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| Bromide SCHEMBL1179197 | 0.96 | PON1 (0.49) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL31238837 | 0.93 | PON1 (0.47) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL29897971 | 0.93 | PON1 (0.47) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL28982038 | 0.91 | PON1 (0.46) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL28235343 | 0.91 | PON1 (0.46) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL385274 | 0.91 | PON1 (0.46) | PON1CYP19A1MAPTCYP11B1CYP11B2 | |
| Bicarbonate SCHEMBL23698535 | 0.89 | PON1 (0.44) | PON1CYP19A1MAPTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735622-A1 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | Illumina, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | BASF SE (DE) | 2026-05-05 | — | — | US | claimed |
| EP-4453243-B1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA INC (US) | 2026-02-11 | — | — | EP | claimed |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BASF SE (DE) | 2025-12-30 | — | — | US | claimed |
| CN-119823109-A | An electrochromic material electrochromic composition and electrochromic device | 吉林大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119637938-A | Nitrogen-doped carbon intercalation MoS2Preparation method and application of @ MCNTs | 德州学院 | 2025-03-18 | — | — | CN | claimed |
| EP-4499870-A1 | COMPOSITIONS AND METHODS FOR IMPROVING SEQUENCING SIGNALS | Illumina, Inc. (US) | 2025-02-05 | — | — | EP | claimed |
| WO-2025003459-A1 | PROTECTING FULLY FUNCTIONAL NUCLEOTIDES FROM DEGRADATION | ILLUMINA, INC. (US) | 2025-01-02 | — | — | WO | claimed |
| US-20240401127-A1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA, INC. | 2024-12-05 | — | — | US | claimed |
| US-20240384327-A1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | ILLUMINA, INC. | 2024-11-21 | — | — | US | claimed |
| US-20160365228-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION | 2016-12-15 | — | — | US | claimed |
| US-9449797-B2 | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RESEARCH CORPORATION (US) | 2016-09-20 | — | — | US | claimed |
| US-9238611-B2 | Process for separating aryl carboxylic acids | RELIANCE INDUSTRIES LIMITED (IN) | 2016-01-19 | — | — | US | claimed |
| US-20140335698-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION (US) | 2014-11-13 | — | — | US | claimed |
| CN-104143494-A | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RES CORP | 2014-11-12 | — | — | CN | claimed |
| US-20120207525-A1 | RESISTANCE HEATING COMPOSITION AND HEATING COMPOSITE, HEATING APPARATUS, AND FUSING APPARATUS, INCLUDING RESISTANCE HEATING COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-08-16 | — | — | US | claimed |
| US-8217100-B2 | Adhesive composition and optical member | CHEIL INDUSTRIES, INC. (KR) | 2012-07-10 | — | — | US | claimed |
| WO-2012084644-A1 | CATALYTIC SYSTEM AND ITS USE FOR THE MANUFACTURE OF VINYL CHLORIDE BY HYDROCHLORINATION OF ACETYLENE | SOLVAY SA (BE) | 2012-06-28 | — | — | WO | claimed |
| US-8002969-B2 | Upgrading crude oil using electrochemically-generated hydrogen | SAUDI ARABIAN OIL COMPANY (SA) | 2011-08-23 | — | — | US | claimed |
| US-20090014123-A1 | Adhesive composition and optical member | Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) | 2009-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617892-B2 | Application of the ring-opening of uretdiones at low temperature and ambient atmosphere | UQCRB, SCO2, UTS2R | PON1 2525/4885CYP19A1 688/4885MAPT 1229/4885 |
| US-20240401127-A1 | PERIODATE COMPOSITIONS AND METHODS FOR CHEMICAL CLEAVAGE OF SURFACE-BOUND POLYNUCLEOTIDES | POLN, PNKP, POLB | PON1 4091/4885CYP19A1 3925/4885MAPT 4319/4885 |
| US-12509547-B2 | Synthesis of linear polyoxazolidinones using uretdiones as diisocyanate component | BMP1, BMP4, PBRM1 | PON1 4465/4885CYP19A1 3290/4885MAPT 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.